S1416 Results: PARPi Benefit in BRCA-like BC
S1416 trial results show PARP inhibitor benefit in "BRCA-like" triple-negative breast cancer
Nab-Paclitaxel and Biliary Tract Cancer OS
Nab-paclitaxel does not extend biliary tract cancer survival, but may benefit some
14.2 Million Life-Years, at $326 Per Year
Clinical trials in adults conducted within the National Cancer Institute’s National Clinical Trials Network over the last four decades are estimated to have extended the lives of patients with cancer in the U.S. by at least 14.2 million life-years, at an estimated cost of only $326 per life-year added
Practice-changing trial results for acute lymphoblastic leukemia (ALL)
The E1910 study showed that, after about 3.5 years of follow-up, 83% of patients who went on to receive additional standard consolidation chemotherapy plus experimental blinatumomab were alive versus 65% of those who received chemotherapy only
NRG Oncology Announces Leadership of New Diversity, Equity, and Inclusion Committee, New Vice Chair for Ancillary Projects Committee
NRG Oncology recently announced the appointed leadership of the organization’s new Diversity, Equity, and Inclusion Committee; the group also announced a change in the leadership of their Ancillary Projects Committee
A unique clinical trial leads to a dramatic decrease in early deaths from the rare and aggressive—yet highly curable—acute promyelocytic leukemia (APL)
The use of a simplified treatment regimen by oncologists, along with management recommendations and 24/7 support provided by a limited and dedicated group of academic disease experts, resulted in a dramatic decrease in early deaths from acute promyelocytic leukemia
The TAILORx trial in over 10,000 women with early breast cancer reaches 12 years of recurrence and survival outcomes
With 12 years of follow-up, an updated analysis from the TAILORx trial confirms the original findings that chemotherapy has no benefit for a large proportion of women with early-stage breast cancer
S1404 Patients Had Better QoL on Pembro
Patients with high-risk melanoma had better quality of life on adjuvant pembrolizumab than on standard adjuvant immunotherapy
SWOG Research Shines at SABCS 2022
SWOG researchers will present 10 abstracts at this year's San Antonio Breast Cancer Symposium, including results from S1207, S1714, and S1007 (RxPONDER), as well as an analysis of ER use by insurance status
Stratification Can Reduce Statistical Power
For phase 2 trials, stratified analysis with more than 1 or 2 stratification factors can significantly reduce a trial's power to detect a positive result