NRG Oncology Appoints Chair & Vice Chair of Radiation Oncology Committee

NRG Oncology has appointed a new Chair and Vice Chair to the organization’s Radiation Oncology Committee

Journal of Clinical Oncology publishes outcomes from the practice-changing DREAMseq trial in patients with advanced melanoma

The DREAMseq trial showed that starting treatment with immunotherapy, followed by targeted therapy if there is disease progression, is the preferred treatment approach for melanoma patients with a BRAF V600 tumor gene mutation

Intensity Modulated Radiotherapy Improved Patient-Reported Outcomes on NRG Oncology Clinical Trial

NRG-RTOG 1203 indicates that patients reported fewer adverse events following intensity-modulated radiotherapy treatment when compared to patients who received the standard 4-field pelvic radiotherapy; clinician-reported data showed no difference in symptoms for patients in the two treatment arms

Neoadjuvant IO Boosts High-Risk Melanoma EFS

Starting pembrolizumab before surgery instead of after significantly improved event-free survival for patients with stage 3-4 melanoma

ECOG-ACRIN completes the first randomized phase 3 clinical trial of neoadjuvant immunotherapy in patients with kidney cancer

Priming the immune system with nivolumab before surgery, then continuing nivolumab, did not improve recurrence-free survival in patients with high-risk renal cell carcinoma

Alliance for Clinical Trials in Oncology Applauds Appointment of Monica M. Bertagnolli as NCI’s New Director

The Alliance for Clinical Trials in Oncology applauds the appointment of its Group Chair and President of the Alliance for Clinical Trials in Oncology Foundation Monica M. Bertagnolli, MD, FACS, FASCO, to serve as President Biden’s pick for Director of the National Cancer Institute

NRG Oncology Appoints Several New Committee Chairs & Vice Chairs

NRG Oncology has announced the appointment of several new Committee Chairs and Vice Chairs representing various areas of the organization

Alliance A021501 Trial Establishes FOLFIRINOX as Preferred Treatment Regimen

In a study of patients with borderline resectable pancreatic cancer, combination chemotherapy with modified FOLFIRINOX before surgery increased survival relative to historical data and compared favorably to FOLFIRINOX plus hypofractionated radiotherapy

Blood publishes long-term outcomes of patients with CLL in the practice-changing E1912 trial

Long-term outcomes are now available from the E1912 trial for patients with chronic lymphocytic leukemia

PSA-Based Endpoints Should Not Be Used as Surrogate Endpoints for Overall Survival in Men with Recurrent Prostate Cancer at this Time

Results from a surrogacy analysis of the NRG-RTOG 9601 trial indicated that biochemical failure was not an adequate surrogate endpoint for overall survival for patients with recurrent prostate cancer following prostatectomy